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ASK Family Kinases Are Required for Optimal NLRP3 Inflammasome Priming
Activation of the multimeric inflammasome complex leads to inflammatory responses to biotic and abiotic triggers. The inflammasome sensor, Nod-like receptor family pyrin domain containing 3 (NLRP3), is activated by a range of stimuli and is tightly regulated to restrict excessive inflammation. Becau...
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| Udgivet i: | Am J Pathol |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Investigative Pathology
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6436110/ https://ncbi.nlm.nih.gov/pubmed/29353059 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.12.006 |
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