DDX3X acts as a live-or-die checkpoint in stressed cells by regulating NLRP3 inflammasome

The cellular stress response has a vital role in regulating homeostasis by modulating cell survival and death. Stress granules are cytoplasmic compartments that enable cells to survive various stressors. Defects in the assembly and disassembly of stress granules are linked to neurodegenerative disea...

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Vydáno v:Nature
Hlavní autoři: Samir, Parimal, Kesavardhana, Sannula, Patmore, Deanna M., Gingras, Sebastien, Malireddi, R. K. Subbarao, Karki, Rajendra, Guy, Clifford S., Briard, Benoit, Place, David E., Bhattacharya, Anannya, Sharma, Bhesh raj, Nourse, Amanda, King, Sharon V., Pitre, Aaron, Burton, Amanda R., Pelletier, Stephane, Gilbertson, Richard J., Kanneganti, Thirumala-Devi
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6980284/
https://ncbi.nlm.nih.gov/pubmed/31511697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1551-2
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