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Tryptophan Probes of TDP-43 C-Terminal Domain Amyloid Formation
Aggregated TAR DNA-binding protein 43 (TDP-43) forms the cytoplasmic hallmarks associated with patients suffering from amyotrophic lateral sclerosis and frontotemporal lobar degeneration with ubiquitin. Under normal conditions, TDP-43 is a 414-amino acid protein; however, aggregates are enriched wit...
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| Publicado no: | J Phys Chem B |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8080960/ https://ncbi.nlm.nih.gov/pubmed/33835818 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.1c00767 |
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