Astrocyte-specific expression of interleukin 23 leads to an aggravated phenotype and enhanced inflammatory response with B cell accumulation in the EAE model

BACKGROUND: Interleukin 23 is a critical cytokine in the pathogenesis of multiple sclerosis. But the local impact of interleukin 23 on the course of neuroinflammation is still not well defined. To further characterize the effect of interleukin 23 on CNS inflammation, we recently described a transgen...

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Опубликовано в: :J Neuroinflammation
Главные авторы: Nitsch, Louisa, Petzinna, Simon, Zimmermann, Julian, Schneider, Linda, Krauthausen, Marius, Heneka, Michael T., Getts, Daniel R., Becker, Albert, Müller, Marcus
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2021
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8080359/
https://ncbi.nlm.nih.gov/pubmed/33906683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-021-02140-z
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