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CXCR3 promotes plaque formation and behavioral deficits in an Alzheimer’s disease model
Chemokines are important modulators of neuroinflammation and neurodegeneration. In the brains of Alzheimer’s disease (AD) patients and in AD animal models, the chemokine CXCL10 is found in high concentrations, suggesting a pathogenic role for this chemokine and its receptor, CXCR3. Recent studies ai...
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| Publicado no: | J Clin Invest |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4382235/ https://ncbi.nlm.nih.gov/pubmed/25500888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI66771 |
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