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CXCR3 modulates glial accumulation and activation in cuprizone-induced demyelination of the central nervous system

BACKGROUND: The functional state of glial cells, like astrocytes and microglia, critically modulates the course of neuroinflammatory and neurodegenerative diseases and can have both detrimental and beneficial effects. Glial cell function is tightly controlled by cellular interactions in which cytoki...

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Autors principals: Krauthausen, Marius, Saxe, Simon, Zimmermann, Julian, Emrich, Michael, Heneka, Michael T, Müller, Marcus
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096537/
https://ncbi.nlm.nih.gov/pubmed/24930935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-11-109
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