Acrolein scavenger dimercaprol offers neuroprotection in an animal model of Parkinson’s disease: implication of acrolein and TRPA1

BACKGROUND: The mechanisms underlying lesions of dopaminergic (DA) neurons, an essential pathology of Parkinson’s disease (PD), are largely unknown, although oxidative stress is recognized as a key factor. We have previously shown that the pro-oxidative aldehyde acrolein is a critical factor in PD p...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Transl Neurodegener
Asıl Yazarlar: Shi, Liangqin, Lin, Yazhou, Jiao, Yucheng, Herr, Seth A., Tang, Jonathan, Rogers, Edmond, Chen, Zhengli, Shi, Riyi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2021
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8080346/
https://ncbi.nlm.nih.gov/pubmed/33910636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40035-021-00239-0
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