Acrolein scavenger dimercaprol offers neuroprotection in an animal model of Parkinson’s disease: implication of acrolein and TRPA1

BACKGROUND: The mechanisms underlying lesions of dopaminergic (DA) neurons, an essential pathology of Parkinson’s disease (PD), are largely unknown, although oxidative stress is recognized as a key factor. We have previously shown that the pro-oxidative aldehyde acrolein is a critical factor in PD p...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Transl Neurodegener
Main Authors: Shi, Liangqin, Lin, Yazhou, Jiao, Yucheng, Herr, Seth A., Tang, Jonathan, Rogers, Edmond, Chen, Zhengli, Shi, Riyi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8080346/
https://ncbi.nlm.nih.gov/pubmed/33910636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40035-021-00239-0
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados