Acrolein-mediated alpha-synuclein pathology involvement in the early post-injury pathogenesis of mild blast-induced Parkinsonian neurodegeneration

Survivors of blast-induced traumatic brain injury (bTBI) have increased susceptibility to Parkinson’s disease (PD), characterized by α-synuclein aggregation and the progressive degeneration of nigrostriatal dopaminergic neurons. Using an established bTBI rat model, we evaluated the changes of α-synu...

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Vydáno v:Mol Cell Neurosci
Hlavní autoři: Acosta, Glen, Race, Nicholas, Herr, Seth, Fernandez, Joseph, Tang, Jonathan, Rogers, Edmond, Shi, Riyi
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6690849/
https://ncbi.nlm.nih.gov/pubmed/31201929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2019.06.004
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