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Chitosan nanoparticle-based neuronal membrane sealing and neuroprotection following acrolein-induced cell injury

BACKGROUND: The highly reactive aldehyde acrolein is a very potent endogenous toxin with a long half-life. Acrolein is produced within cells after insult, and is a central player in slow and progressive "secondary injury" cascades. Indeed, acrolein-biomolecule complexes formed by cross-lin...

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Detalhes bibliográficos
Main Authors: Cho, Youngnam, Shi, Riyi, Ben Borgens, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824642/
https://ncbi.nlm.nih.gov/pubmed/20205817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1754-1611-4-2
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