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Acrolein contributes to TRPA1 up-regulation in peripheral and central sensory hypersensitivity following spinal cord injury
Acrolein, an endogenous aldehyde, has been shown to be involved in sensory hypersensitivity after rat SCI, for which the pathogenesis is unclear. Acrolein can directly activate a pro-algesic transient receptor protein ankyrin 1 (TRPA1) channel that exists in sensory neurons. Both acrolein and TRPA1...
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| Publicado no: | J Neurochem |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4715756/ https://ncbi.nlm.nih.gov/pubmed/26365991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13352 |
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