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Neuroprotective role of hydralazine in rat spinal cord injury-attenuation of acrolein-mediated damage

Acrolein, an α,β-unsaturated aldehyde and a reactive product of lipid peroxidation, has been suggested as a key factor in neural post-traumatic secondary injury in SCI, mainly based on in vitro and ex vivo evidence. Here we demonstrate an increase of acrolein up to 300%; the elevation lasted at leas...

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Bibliografiske detaljer
Main Authors: Park, Jonghyuck, Zheng, Lingxing, Marquis, Andrew, Walls, Michael, Duerstock, Brad, Pond, Amber, Alvarez, Sascha Vega, He, Wang, Ouyang, Zheng, Shi, Riyi
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3980042/
https://ncbi.nlm.nih.gov/pubmed/24286176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12628
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