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Neuroprotective role of hydralazine in rat spinal cord injury-attenuation of acrolein-mediated damage
Acrolein, an α,β-unsaturated aldehyde and a reactive product of lipid peroxidation, has been suggested as a key factor in neural post-traumatic secondary injury in SCI, mainly based on in vitro and ex vivo evidence. Here we demonstrate an increase of acrolein up to 300%; the elevation lasted at leas...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3980042/ https://ncbi.nlm.nih.gov/pubmed/24286176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12628 |
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