The Nek2 centrosome-mitotic kinase contributes to the mesenchymal state, cell invasion, and migration of triple-negative breast cancer cells

Nek2 (NIMA‐related kinase 2) is a serine/threonine-protein kinase that localizes to centrosomes and kinetochores, controlling centrosome separation, chromosome attachments to kinetochores, and the spindle assembly checkpoint. These processes prevent centrosome amplification (CA), mitotic dysfunction...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Rivera-Rivera, Yainyrette, Marina, Mihaela, Jusino, Shirley, Lee, Miyoung, Velázquez, Jaleisha Vélez, Chardón-Colón, Camille, Vargas, Geraldine, Padmanabhan, Jaya, Chellappan, Srikumar P., Saavedra, Harold I.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2021
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8079711/
https://ncbi.nlm.nih.gov/pubmed/33907253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-88512-0
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