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Nek2 phosphorylates and stabilizes β-catenin at mitotic centrosomes downstream of Plk1

β-Catenin is a multifunctional protein with critical roles in cell–cell adhesion, Wnt signaling, and the centrosome cycle. Whereas the regulation of β-catenin in cell–cell adhesion and Wnt signaling are well understood, how β-catenin is regulated at the centrosome is not. NIMA-related protein kinase...

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Detalhes bibliográficos
Main Authors: Mbom, Bertrade C., Siemers, Kathleen A., Ostrowski, Maggie A., Nelson, W. James, Barth, Angela I. M.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3967981/
https://ncbi.nlm.nih.gov/pubmed/24501426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-06-0349
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