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The E2F activators control multiple mitotic regulators and maintain genomic integrity through Sgo1 and BubR1
The E2F1, E2F2, and E2F3a transcriptional activators control proliferation. However, how the E2F activators regulate mitosis to maintain genomic integrity is unclear. Centrosome amplification (CA) and unregulated spindle assembly checkpoint (SAC) are major generators of aneuploidy and chromosome ins...
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| Udgivet i: | Oncotarget |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Impact Journals LLC
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5652806/ https://ncbi.nlm.nih.gov/pubmed/29100415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20765 |
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