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Haplo-insufficiency of both BubR1 and SGO1 accelerates cellular senescence
BACKGROUND: Spindle assembly checkpoint components BubR1 and Sgo1 play a key role in the maintenance of chromosomal instability during cell division. These proteins function to block the anaphase entry until all condensed chromosomes have been attached by the microtubules emanating from both spindle...
保存先:
| 出版年: | J Hematol Oncol |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4743409/ https://ncbi.nlm.nih.gov/pubmed/26847209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-016-0238-5 |
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