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Spliceosomal Factor Mutations and Mis-splicing in MDS

Somatic, heterozygous missense and nonsense mutations in at least eight proteins that function in the spliceosome are found at high frequency in MDS patients. These proteins act at various steps in the process of splicing by the spliceosome and lead to characteristic alterations in the alternative s...

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Foilsithe in:Best Pract Res Clin Haematol
Main Authors: Hershberger, Courtney E., Daniels, Noah, Padgett, Richard A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8078562/
https://ncbi.nlm.nih.gov/pubmed/33038983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.beha.2020.101199
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