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Spliceosomal Factor Mutations and Mis-splicing in MDS

Somatic, heterozygous missense and nonsense mutations in at least eight proteins that function in the spliceosome are found at high frequency in MDS patients. These proteins act at various steps in the process of splicing by the spliceosome and lead to characteristic alterations in the alternative s...

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Detalhes bibliográficos
Publicado no:Best Pract Res Clin Haematol
Main Authors: Hershberger, Courtney E., Daniels, Noah, Padgett, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8078562/
https://ncbi.nlm.nih.gov/pubmed/33038983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.beha.2020.101199
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