Hypoxia Inducible Factor 1A Supports a Pro-Fibrotic Phenotype Loop in Idiopathic Pulmonary Fibrosis

Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease with poor prognosis. The IPF-conditioned matrix (IPF-CM) system enables the study of matrix–fibroblast interplay. While effective at slowing fibrosis, nintedanib has limitations and the mechanism is not fully elucidated. In the curren...

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Pubblicato in:Int J Mol Sci
Autori principali: Epstein Shochet, Gali, Bardenstein-Wald, Becky, McElroy, Mary, Kukuy, Andrew, Surber, Mark, Edelstein, Evgeny, Pertzov, Barak, Kramer, Mordechai Reuven, Shitrit, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8078165/
https://ncbi.nlm.nih.gov/pubmed/33805152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22073331
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