Integrin alpha-5 silencing leads to myofibroblastic differentiation in IPF-derived human lung fibroblasts

BACKGROUND AND OBJECTIVE: The term ‘fibroblast’ covers a heterogeneous cell population in idiopathic pulmonary fibrosis (IPF). The fibroblasts are considered as main effector cells, because they promote disease progression by releasing exaggerated amounts of extracellular matrix proteins and modifyi...

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Vydáno v:Ther Adv Chronic Dis
Hlavní autoři: Shochet, Gali Epstein, Brook, Elizabetha, Bardenstein-Wald, Becky, Grobe, Hanna, Edelstein, Evgeny, Israeli-Shani, Lilach, Shitrit, David
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2020
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7315658/
https://ncbi.nlm.nih.gov/pubmed/32637060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2040622320936023
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