Integrin alpha-5 silencing leads to myofibroblastic differentiation in IPF-derived human lung fibroblasts

BACKGROUND AND OBJECTIVE: The term ‘fibroblast’ covers a heterogeneous cell population in idiopathic pulmonary fibrosis (IPF). The fibroblasts are considered as main effector cells, because they promote disease progression by releasing exaggerated amounts of extracellular matrix proteins and modifyi...

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Detalles Bibliográficos
Publicado en:Ther Adv Chronic Dis
Autores principales: Shochet, Gali Epstein, Brook, Elizabetha, Bardenstein-Wald, Becky, Grobe, Hanna, Edelstein, Evgeny, Israeli-Shani, Lilach, Shitrit, David
Formato: Artigo
Lenguaje:Inglês
Publicado: SAGE Publications 2020
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7315658/
https://ncbi.nlm.nih.gov/pubmed/32637060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2040622320936023
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