Fibroblast paracrine TNF-α signaling elevates integrin A5 expression in idiopathic pulmonary fibrosis (IPF)

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease with a poor prognosis. Inflammatory cytokines play a significant role in IPF pathology. However, the fibroblast itself is also believed to be the primary effector in IPF. We hypothesized that the fibroblasts themselves sec...

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Podrobná bibliografie
Vydáno v:Respir Res
Hlavní autoři: Epstein Shochet, Gali, Brook, Elizabetha, Israeli-Shani, Lilach, Edelstein, Evgeny, Shitrit, David
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5477311/
https://ncbi.nlm.nih.gov/pubmed/28629363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-017-0606-x
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