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TGF-β pathway activation by idiopathic pulmonary fibrosis (IPF) fibroblast derived soluble factors is mediated by IL-6 trans-signaling

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a chronic and ultimately fatal disease characterized by a progressive decline in lung function. Fibrotic diseases, such as IPF, are characterized by uncontrolled activation of fibroblasts. Since the microenvironment is known to affect cell behavior,...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Respir Res
Main Authors: Epstein Shochet, Gali, Brook, Elizabetha, Bardenstein-Wald, Becky, Shitrit, David
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2020
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7029598/
https://ncbi.nlm.nih.gov/pubmed/32070329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-020-1319-0
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