The Neuroprotective Beta Amyloid Hexapeptide Core Reverses Deficits in Synaptic Plasticity in the 5xFAD APP/PS1 Mouse Model

Alzheimer’s disease (AD) is the most common cause of dementia in the aging population. Evidence implicates elevated soluble oligomeric Aβ as one of the primary triggers during the prodromic phase leading to AD, effected largely via hyperphosphorylation of the microtubule-associated protein tau. At l...

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Detalles Bibliográficos
Publicado en:Front Mol Neurosci
Autores principales: Forest, Kelly H., Taketa, Ruth, Arora, Komal, Todorovic, Cedomir, Nichols, Robert A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8075567/
https://ncbi.nlm.nih.gov/pubmed/33912008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2021.576038
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