Single-cell characterization of a model of poly I:C-stimulated peripheral blood mononuclear cells in severe asthma

BACKGROUND: Asthma has been associated with impaired interferon response. Multiple cell types have been implicated in such response impairment and may be responsible for asthma immunopathology. However, existing models to study the immune response in asthma are limited by bulk profiling of cells. Ou...

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Veröffentlicht in:Respir Res
Hauptverfasser: Chen, Ailu, Diaz-Soto, Maria P., Sanmamed, Miguel F., Adams, Taylor, Schupp, Jonas C., Gupta, Amolika, Britto, Clemente, Sauler, Maor, Yan, Xiting, Liu, Qing, Nino, Gustavo, Cruz, Charles S. Dela, Chupp, Geoffrey L., Gomez, Jose L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2021
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8074196/
https://ncbi.nlm.nih.gov/pubmed/33902571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-021-01709-9
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