Single-cell characterization of a model of poly I:C-stimulated peripheral blood mononuclear cells in severe asthma

BACKGROUND: Asthma has been associated with impaired interferon response. Multiple cell types have been implicated in such response impairment and may be responsible for asthma immunopathology. However, existing models to study the immune response in asthma are limited by bulk profiling of cells. Ou...

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: Chen, Ailu, Diaz-Soto, Maria P., Sanmamed, Miguel F., Adams, Taylor, Schupp, Jonas C., Gupta, Amolika, Britto, Clemente, Sauler, Maor, Yan, Xiting, Liu, Qing, Nino, Gustavo, Cruz, Charles S. Dela, Chupp, Geoffrey L., Gomez, Jose L.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8074196/
https://ncbi.nlm.nih.gov/pubmed/33902571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-021-01709-9
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