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Single-cell characterization of a model of poly I:C-stimulated peripheral blood mononuclear cells in severe asthma

BACKGROUND: Asthma has been associated with impaired interferon response. Multiple cell types have been implicated in such response impairment and may be responsible for asthma immunopathology. However, existing models to study the immune response in asthma are limited by bulk profiling of cells. Ou...

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Pubblicato in:Respir Res
Autori principali: Chen, Ailu, Diaz-Soto, Maria P., Sanmamed, Miguel F., Adams, Taylor, Schupp, Jonas C., Gupta, Amolika, Britto, Clemente, Sauler, Maor, Yan, Xiting, Liu, Qing, Nino, Gustavo, Cruz, Charles S. Dela, Chupp, Geoffrey L., Gomez, Jose L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8074196/
https://ncbi.nlm.nih.gov/pubmed/33902571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-021-01709-9
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