Single-cell characterization of a model of poly I:C-stimulated peripheral blood mononuclear cells in severe asthma

BACKGROUND: Asthma has been associated with impaired interferon response. Multiple cell types have been implicated in such response impairment and may be responsible for asthma immunopathology. However, existing models to study the immune response in asthma are limited by bulk profiling of cells. Ou...

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Bibliografiske detaljer
Udgivet i:Respir Res
Main Authors: Chen, Ailu, Diaz-Soto, Maria P., Sanmamed, Miguel F., Adams, Taylor, Schupp, Jonas C., Gupta, Amolika, Britto, Clemente, Sauler, Maor, Yan, Xiting, Liu, Qing, Nino, Gustavo, Cruz, Charles S. Dela, Chupp, Geoffrey L., Gomez, Jose L.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8074196/
https://ncbi.nlm.nih.gov/pubmed/33902571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-021-01709-9
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