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Multi-Enzymatic Cascades in the Synthesis of Modified Nucleosides: Comparison of the Thermophilic and Mesophilic Pathways

A comparative study of the possibilities of using ribokinase → phosphopentomutase → nucleoside phosphorylase cascades in the synthesis of modified nucleosides was carried out. Recombinant phosphopentomutase from Thermus thermophilus HB27 was obtained for the first time: a strain producing a soluble...

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Dettagli Bibliografici
Pubblicato in:Biomolecules
Autori principali: Fateev, Ilja V., Kostromina, Maria A., Abramchik, Yuliya A., Eletskaya, Barbara Z., Mikheeva, Olga O., Lukoshin, Dmitry D., Zayats, Evgeniy A., Berzina, Maria Ya., Dorofeeva, Elena V., Paramonov, Alexander S., Kayushin, Alexey L., Konstantinova, Irina D., Esipov, Roman S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8073115/
https://ncbi.nlm.nih.gov/pubmed/33923608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11040586
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