A Cascade of Thermophilic Enzymes As an Approach to the Synthesis of Modified Nucleotides

We propose a new approach for the synthesis of biologically important nucleotides which includes a multi-enzymatic cascade conversion of D-pentoses into purine nucleotides. The approach exploits nucleic acid exchange enzymes from thermophilic microorganisms: ribokinase, phosphoribosylpyrophosphate s...

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Publicat a:Acta Naturae
Autors principals: Esipov, R. S., Abramchik, Yu. A., Fateev, I. V., Konstantinova, I. D., Kostromina, M. A., Muravyova, T. I., Artemova, K. G., Miroshnikov, A. I.
Format: Artigo
Idioma:Inglês
Publicat: A.I. Gordeyev 2016
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5199209/
https://ncbi.nlm.nih.gov/pubmed/28050269
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