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Multi-Enzymatic Cascades in the Synthesis of Modified Nucleosides: Comparison of the Thermophilic and Mesophilic Pathways

A comparative study of the possibilities of using ribokinase → phosphopentomutase → nucleoside phosphorylase cascades in the synthesis of modified nucleosides was carried out. Recombinant phosphopentomutase from Thermus thermophilus HB27 was obtained for the first time: a strain producing a soluble...

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Publicat a:Biomolecules
Autors principals: Fateev, Ilja V., Kostromina, Maria A., Abramchik, Yuliya A., Eletskaya, Barbara Z., Mikheeva, Olga O., Lukoshin, Dmitry D., Zayats, Evgeniy A., Berzina, Maria Ya., Dorofeeva, Elena V., Paramonov, Alexander S., Kayushin, Alexey L., Konstantinova, Irina D., Esipov, Roman S.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8073115/
https://ncbi.nlm.nih.gov/pubmed/33923608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11040586
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