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A G316A Polymorphism in the Ornithine Decarboxylase Gene Promoter Modulates MYCN-Driven Childhood Neuroblastoma

SIMPLE SUMMARY: Neuroblastoma is a devasting childhood cancer in which multiple copies (amplification) of the cancer-causing gene MYCN strongly predict poor outcome. Neuroblastomas are reliant on high levels of cellular components called polyamines for their growth and malignant behavior, and the ge...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Cancers (Basel)
मुख्य लेखकों: Gamble, Laura D., Purgato, Stefania, Henderson, Michelle J., Di Giacomo, Simone, Russell, Amanda J., Pigini, Paolo, Murray, Jayne, Valli, Emanuele, Milazzo, Giorgio, Giorgi, Federico M., Cowley, Mark, Ashton, Lesley J., Bhalshankar, Jaydutt, Schleiermacher, Gudrun, Rihani, Ali, Van Maerken, Tom, Vandesompele, Jo, Speleman, Frank, Versteeg, Rogier, Koster, Jan, Eggert, Angelika, Noguera, Rosa, Stallings, Raymond L., Tonini, Gian Paolo, Fong, Kwun, Vaksman, Zalman, Diskin, Sharon J., Maris, John M., London, Wendy B., Marshall, Glenn M., Ziegler, David S., Hogarty, Michael D., Perini, Giovanni, Norris, Murray D., Haber, Michelle
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: MDPI 2021
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC8069650/
https://ncbi.nlm.nih.gov/pubmed/33918978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13081807
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