Chirality of Novel Bitopic Agonists Determines Unique Pharmacology at the Dopamine D3 Receptor

The dopamine D2/D3 receptor (D(2)R/D(3)R) agonists are used as therapeutics for Parkinson’s disease (PD) and other motor disorders. Selective targeting of D(3)R over D(2)R is attractive because of D(3)R’s restricted tissue distribution with potentially fewer side-effects and its putative neuroprotec...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Adhikari, Pramisha, Xie, Bing, Semeano, Ana, Bonifazi, Alessandro, Battiti, Francisco O., Newman, Amy H., Yano, Hideaki, Shi, Lei
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Brief Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8069330/
https://ncbi.nlm.nih.gov/pubmed/33924613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11040570
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados