hTERT-Driven Immortalization of RDEB Fibroblast and Keratinocyte Cell Lines Followed by Cre-Mediated Transgene Elimination

The recessive form of dystrophic epidermolysis bullosa (RDEB) is a crippling disease caused by impairments in the junctions of the dermis and the basement membrane of the epidermis. Using ectopic expression of hTERT/hTERT + BMI-1 in primary cells, we developed expansible cultures of RDEB fibroblasts...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Int J Mol Sci
Egile Nagusiak: Evtushenko, Nadezhda A., Beilin, Arkadii K., Dashinimaev, Erdem B., Ziganshin, Rustam H., Kosykh, Anastasiya V., Perfilov, Maxim M., Rippa, Alexandra L., Alpeeva, Elena V., Vasiliev, Andrey V., Vorotelyak, Ekaterina A., Gurskaya, Nadya G.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2021
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8067634/
https://ncbi.nlm.nih.gov/pubmed/33916959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22083809
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