hTERT-Driven Immortalization of RDEB Fibroblast and Keratinocyte Cell Lines Followed by Cre-Mediated Transgene Elimination

The recessive form of dystrophic epidermolysis bullosa (RDEB) is a crippling disease caused by impairments in the junctions of the dermis and the basement membrane of the epidermis. Using ectopic expression of hTERT/hTERT + BMI-1 in primary cells, we developed expansible cultures of RDEB fibroblasts...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Int J Mol Sci
Prif Awduron: Evtushenko, Nadezhda A., Beilin, Arkadii K., Dashinimaev, Erdem B., Ziganshin, Rustam H., Kosykh, Anastasiya V., Perfilov, Maxim M., Rippa, Alexandra L., Alpeeva, Elena V., Vasiliev, Andrey V., Vorotelyak, Ekaterina A., Gurskaya, Nadya G.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2021
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8067634/
https://ncbi.nlm.nih.gov/pubmed/33916959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22083809
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