GSK-3β Can Regulate the Sensitivity of MIA-PaCa-2 Pancreatic and MCF-7 Breast Cancer Cells to Chemotherapeutic Drugs, Targeted Therapeutics and Nutraceuticals

Glycogen synthase kinase-3 (GSK-3) is a regulator of signaling pathways. KRas is frequently mutated in pancreatic cancers. The growth of certain pancreatic cancers is KRas-dependent and can be suppressed by GSK-3 inhibitors, documenting a link between KRas and GSK-3. To further elucidate the roles o...

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Udgivet i:Cells
Main Authors: Abrams, Stephen L., Akula, Shaw M., Meher, Akshaya K., Steelman, Linda S., Gizak, Agnieszka, Duda, Przemysław, Rakus, Dariusz, Martelli, Alberto M., Ratti, Stefano, Cocco, Lucio, Montalto, Giuseppe, Cervello, Melchiorre, Ruvolo, Peter, Libra, Massimo, Falzone, Luca, Candido, Saverio, McCubrey, James A.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8067414/
https://ncbi.nlm.nih.gov/pubmed/33917370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10040816
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