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Mitochondrion-Dependent Cell Death in TDP-43 Proteinopathies
In the last decade, pieces of evidence for TDP-43-mediated mitochondrial dysfunction in neurodegenerative diseases have accumulated. In patient samples, in vitro and in vivo models have shown mitochondrial accumulation of TDP-43, concomitantly with hallmarks of mitochondrial destabilization, such as...
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| Publicado en: | Biomedicines |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8066287/ https://ncbi.nlm.nih.gov/pubmed/33918437 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9040376 |
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