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Mechanisms of TDP-43 Proteinopathy Onset and Propagation

TDP-43 is an RNA-binding protein that has been robustly linked to the pathogenesis of a number of neurodegenerative disorders, including amyotrophic lateral sclerosis and frontotemporal dementia. While mutations in the TARDBP gene that codes for the protein have been identified as causing disease in...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Chen, Han-Jou, Mitchell, Jacqueline C.
Format: Artigo
Language:Inglês
Published: MDPI 2021
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8199531/
https://ncbi.nlm.nih.gov/pubmed/34199367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22116004
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