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TDP-43 Proteinopathy and ALS: Insights into Disease Mechanisms and Therapeutic Targets

Therapeutic options for patients with amyotrophic lateral sclerosis (ALS) are currently limited. However, recent studies show that almost all cases of ALS, as well as tau-negative frontotemporal dementia (FTD), share a common neuropathology characterized by the deposition of TAR-DNA binding protein...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Neurotherapeutics
Main Authors: Scotter, Emma L., Chen, Han-Jou, Shaw, Christopher E.
Format: Artigo
Jezik:Inglês
Izdano: Springer US 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4404432/
https://ncbi.nlm.nih.gov/pubmed/25652699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-015-0338-x
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