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TDP-43 Proteinopathy and ALS: Insights into Disease Mechanisms and Therapeutic Targets

Therapeutic options for patients with amyotrophic lateral sclerosis (ALS) are currently limited. However, recent studies show that almost all cases of ALS, as well as tau-negative frontotemporal dementia (FTD), share a common neuropathology characterized by the deposition of TAR-DNA binding protein...

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Vydáno v:Neurotherapeutics
Hlavní autoři: Scotter, Emma L., Chen, Han-Jou, Shaw, Christopher E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4404432/
https://ncbi.nlm.nih.gov/pubmed/25652699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-015-0338-x
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