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Targeting Dietary and Microbial Tryptophan-Indole Metabolism as Therapeutic Approaches to Colon Cancer

Tryptophan metabolism, via the kynurenine (Kyn) pathway, and microbial transformation of tryptophan to indolic compounds are fundamental for host health; both of which are altered in colon carcinogenesis. Alterations in tryptophan metabolism begin early in colon carcinogenesis as an adaptive mechani...

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Detalhes bibliográficos
Publicado no:Nutrients
Main Authors: Wyatt, Madhur, Greathouse, K. Leigh
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8066279/
https://ncbi.nlm.nih.gov/pubmed/33916690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu13041189
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