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The therapeutic potential of targeting tryptophan catabolism in cancer

Based on its effects on both tumour cell intrinsic malignant properties as well as anti-tumour immune responses, tryptophan catabolism has emerged as an important metabolic regulator of cancer progression. Three enzymes, indoleamine-2,3-dioxygenase 1 and 2 (IDO1/2) and tryptophan-2,3-dioxygenase (TD...

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Dades bibliogràfiques
Publicat a:Br J Cancer
Autors principals: Opitz, Christiane A., Somarribas Patterson, Luis F., Mohapatra, Soumya R., Dewi, Dyah L., Sadik, Ahmed, Platten, Michael, Trump, Saskia
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6964670/
https://ncbi.nlm.nih.gov/pubmed/31819194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-019-0664-6
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