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The therapeutic potential of targeting tryptophan catabolism in cancer
Based on its effects on both tumour cell intrinsic malignant properties as well as anti-tumour immune responses, tryptophan catabolism has emerged as an important metabolic regulator of cancer progression. Three enzymes, indoleamine-2,3-dioxygenase 1 and 2 (IDO1/2) and tryptophan-2,3-dioxygenase (TD...
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| Veröffentlicht in: | Br J Cancer |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6964670/ https://ncbi.nlm.nih.gov/pubmed/31819194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-019-0664-6 |
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