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Age and insulin-like growth factor-1 impact PCNA monoubiquitination in UVB-irradiated human skin
Nonmelanoma skin cancers occur primarily in individuals over the age of 60 and are characterized by an abundance of ultraviolet (UV) signature mutations in keratinocyte DNA. Though geriatric skin removes UV photoproducts from DNA less efficiently than young adult skin, it is not known whether the ut...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8065225/ https://ncbi.nlm.nih.gov/pubmed/33753168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100570 |
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