UVB-induced Senescence in Human Keratinocytes Requires a Functional Insulin-like Growth Factor-1 Receptor and p53

To cope with the frequent exposure to carcinogenic UV B (UVB) wavelengths found in sunlight, keratinocytes have acquired extensive protective measures to handle UVB-induced DNA damage. Recent in vitro and epidemiological data suggest one these protective mechanisms is dependent on the functional sta...

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Bibliographic Details
Main Authors: Lewis, Davina A., Yi, Qiaofang, Travers, Jeffrey B., Spandau, Dan F
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2008
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2291419/
https://ncbi.nlm.nih.gov/pubmed/18216278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-10-1041
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