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Comparative analysis of assays to measure CAR T cell–mediated cytotoxicity

The antitumor efficacy of genetically engineered “living drugs,” including chimeric antigen receptor and T-cell receptor T cells, is influenced by their activation, proliferation, inhibition, and exhaustion. A sensitive and reproducible cytotoxicity assay that collectively reflects these functions i...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Protoc
Egile Nagusiak: Kiesgen, Stefan, Messinger, John C., Chintala, Navin K., Tano, Zachary, Adusumilli, Prasad S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2021
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8064272/
https://ncbi.nlm.nih.gov/pubmed/33589826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41596-020-00467-0
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