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Comparative analysis of assays to measure CAR T cell–mediated cytotoxicity
The antitumor efficacy of genetically engineered “living drugs,” including chimeric antigen receptor and T-cell receptor T cells, is influenced by their activation, proliferation, inhibition, and exhaustion. A sensitive and reproducible cytotoxicity assay that collectively reflects these functions i...
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| Publicado no: | Nat Protoc |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8064272/ https://ncbi.nlm.nih.gov/pubmed/33589826 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41596-020-00467-0 |
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