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The Telomeric Protein TRF2 Regulates Replication Origin Activity within Pericentromeric Heterochromatin
Heterochromatic regions render the replication process particularly difficult due to the high level of chromatin compaction and the presence of repeated DNA sequences. In humans, replication through pericentromeric heterochromatin requires the binding of a complex formed by the telomeric factor TRF2...
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| Udgivet i: | Life (Basel) |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8063955/ https://ncbi.nlm.nih.gov/pubmed/33804994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/life11040267 |
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