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α-Crystallins in the vertebrate eye lens: Complex oligomers and molecular chaperones
α-crystallins are small heat-shock proteins that act as holdase chaperones. In humans, αA is expressed only in the eye lens, while αB is found in many tissues. α-crystallins have a central domain flanked by flexible extensions and form dynamic, heterogenous oligomers. Structural models show that bot...
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| Udgivet i: | Annu Rev Phys Chem |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8062273/ https://ncbi.nlm.nih.gov/pubmed/33321054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-physchem-090419-121428 |
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