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The structure and oxidation of the eye lens chaperone αA-crystallin

The small heat shock protein (sHsp) αA-crystallin is a molecular chaperone important for the optical properties of the vertebrate eye lens. It forms heterogeneous oligomeric ensembles. We determined the structures of human αA-crystallin oligomers combining cryo-electron microscopy, cross-linking/mas...

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Bibliografske podrobnosti
izdano v:Nat Struct Mol Biol
Main Authors: Kaiser, Christoph J. O., Peters, Carsten, Schmid, Philipp W. N., Stavropoulou, Maria, Zou, Juan, Dahiya, Vinay, Mymrikov, Evgeny V., Rockel, Beate, Asami, Sam, Haslbeck, Martin, Rappsilber, Juri, Reif, Bernd, Zacharias, Martin, Buchner, Johannes, Weinkauf, Sevil
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7115824/
https://ncbi.nlm.nih.gov/pubmed/31792453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-019-0332-9
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