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The structure and oxidation of the eye lens chaperone αA-crystallin

The small heat shock protein (sHsp) αA-crystallin is a molecular chaperone important for the optical properties of the vertebrate eye lens. It forms heterogeneous oligomeric ensembles. We determined the structures of human αA-crystallin oligomers combining cryo-electron microscopy, cross-linking/mas...

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書誌詳細
出版年:Nat Struct Mol Biol
主要な著者: Kaiser, Christoph J. O., Peters, Carsten, Schmid, Philipp W. N., Stavropoulou, Maria, Zou, Juan, Dahiya, Vinay, Mymrikov, Evgeny V., Rockel, Beate, Asami, Sam, Haslbeck, Martin, Rappsilber, Juri, Reif, Bernd, Zacharias, Martin, Buchner, Johannes, Weinkauf, Sevil
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7115824/
https://ncbi.nlm.nih.gov/pubmed/31792453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-019-0332-9
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