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An alternative splice variant of human αA-crystallin modulates the oligomer ensemble and the chaperone activity of α-crystallins
In humans, ten genes encode small heat shock proteins with lens αA-crystallin and αB-crystallin representing two of the most prominent members. The canonical isoforms of αA-crystallin and αB-crystallin collaborate in the eye lens to prevent irreversible protein aggregation and preserve visual acuity...
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| Pubblicato in: | Cell Stress Chaperones |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Springer Netherlands
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5465031/ https://ncbi.nlm.nih.gov/pubmed/28214988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-017-0772-2 |
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