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Multiple molecular architectures of the eye lens chaperone αB-crystallin elucidated by a triple hybrid approach
The molecular chaperone αB-crystallin, the major player in maintaining the transparency of the eye lens, prevents stress-damaged and aging lens proteins from aggregation. In nonlenticular cells, it is involved in various neurological diseases, diabetes, and cancer. Given its structural plasticity an...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3251151/ https://ncbi.nlm.nih.gov/pubmed/22143763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1111014108 |
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