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Functional Amyloid Protection in the Eye Lens: Retention of α-Crystallin Molecular Chaperone Activity after Modification into Amyloid Fibrils

Amyloid fibril formation occurs from a wide range of peptides and proteins and is typically associated with a loss of protein function and/or a gain of toxic function, as the native structure of the protein undergoes major alteration to form a cross β-sheet array. It is now well recognised that some...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Garvey, Megan, Ecroyd, Heath, Ray, Nicholas J., Gerrard, Juliet A., Carver, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5618248/
https://ncbi.nlm.nih.gov/pubmed/28895938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom7030067
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